AuCl(3)-catalyzed synthesis of highly substituted furans from 2-(1-alkynyl)-2-alken-1-ones

Tuanli Yao; Xiaoxia Zhang; Richard C Larock

doi:10.1021/ja0466964

AuCl(3)-catalyzed synthesis of highly substituted furans from 2-(1-alkynyl)-2-alken-1-ones

J Am Chem Soc. 2004 Sep 15;126(36):11164-5. doi: 10.1021/ja0466964.

Authors

Tuanli Yao¹, Xiaoxia Zhang, Richard C Larock

Affiliation

¹ Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.

PMID: 15355093
DOI: 10.1021/ja0466964

Abstract

Highly substituted furans have been synthesized by the reaction of 2-(1-alkynyl)-2-alken-1-ones and various nucleophiles under very mild reaction conditions in good to excellent yields. Gold and some other transition metals are efficient catalysts for this reaction.