One hundred requests for predictive testing for Huntington's disease

Clin Genet. 1992 Jun;41(6):326-30. doi: 10.1111/j.1399-0004.1992.tb03407.x.


In Grampian region, the first 100 requests for predictive testing for Huntington's disease have been analysed. Forty-five presymptomatic predictive test results have been given, eleven families have made a decision to undergo prenatal exclusion tests, and so far eleven pregnancies have been investigated using chorion villus biopsy. This paper presents the protocol used and a descriptive analysis of those receiving results, those choosing to leave the programme, and those unable to complete it because of an unsuitable family structure or unco-operative relatives.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Chi-Square Distribution
  • Female
  • Genetic Counseling
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Huntington Disease / diagnosis*
  • Huntington Disease / genetics
  • Huntington Disease / psychology
  • Informed Consent
  • Male
  • Predictive Value of Tests
  • Scotland