Proton magnetic resonance spectroscopy and magnetic resonance imaging findings in a patient with central nervous system paracoccidioidomycosis

J Neuroimaging. 2004 Oct;14(4):377-9. doi: 10.1177/1051228404267053.


The authors describe a patient with brain paracoccidioidomycosis whose magnetic resonance image (MRI) showed multiple hypointense lesions on T2-weighted images with peripheral enhancement after gadolinium injection. Single-voxel proton magnetic resonance spectroscopy (1H-MRS) of one of the lesions showed 2 peaks at 0.9 and 1.32 ppm, corresponding to lipid signals, indicating intense necrosis. The other characteristic peaks of 1H-MRS were undifferentiated from baseline. These findings, although not specific, may help to differentiate fungal abscess from tumoral lesions and other types of abscess.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Central Nervous System Diseases / diagnosis*
  • Central Nervous System Diseases / microbiology*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Spectroscopy*
  • Male
  • Paracoccidioidomycosis / diagnosis*