Food allergy in irritable bowel syndrome: new facts and old fallacies

Gut. 2004 Oct;53(10):1391-3. doi: 10.1136/gut.2004.044990.


The notion of food allergy in irritable bowel syndrome (IBS) is not new. However, recent evidence suggests significant reduction in IBS symptom severity in patients on elimination diets, provided that dietary elimination is based on foods against which the individual had raised IgG antibodies. These findings should encourage studies dissecting the mechanisms responsible for IgG production against dietary antigens and their putative role in IBS

Publication types

  • Comment

MeSH terms

  • Food Hypersensitivity / complications*
  • Food Hypersensitivity / immunology
  • Humans
  • Immunoglobulin G / biosynthesis
  • Irritable Bowel Syndrome / etiology*
  • Irritable Bowel Syndrome / immunology


  • Immunoglobulin G