Osteonecrosis in children with severe acute respiratory syndrome

Pediatr Infect Dis J. 2004 Sep;23(9):888-90. doi: 10.1097/01.inf.0000137570.37856.ea.

Abstract

Osteonecrosis is a debilitating bone disease affecting adults who have recovered from severe acute respiratory syndrome in Hong Kong and China, but there are no data on its prevalence in children. We report 5 children with magnetic resonance imaging evidence of osteonecrosis. In view of the high prevalence and asymptomatic presentation of osteonecrosis, we suggest magnetic resonance imaging screening for osteonecrosis in children with severe acute respiratory syndrome.

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents
  • Child
  • Cohort Studies
  • Drug Therapy, Combination / therapeutic use
  • Female
  • Follow-Up Studies
  • Hip Joint / pathology
  • Hong Kong / epidemiology
  • Humans
  • Knee Joint / pathology
  • Magnetic Resonance Imaging / methods
  • Male
  • Osteonecrosis / diagnosis*
  • Osteonecrosis / drug therapy
  • Osteonecrosis / epidemiology*
  • Prednisolone / therapeutic use
  • Risk Assessment
  • SARS Virus / isolation & purification
  • Sampling Studies
  • Severe Acute Respiratory Syndrome / diagnosis*
  • Severe Acute Respiratory Syndrome / drug therapy
  • Severe Acute Respiratory Syndrome / epidemiology*
  • Severity of Illness Index

Substances

  • Anti-Bacterial Agents
  • Prednisolone