Cell Motility Under the Microscope: Vorsprung Durch Technik

Nat Rev Mol Cell Biol. 2004 Aug;5(8):667-72. doi: 10.1038/nrm1439.


The fashion today is to disparage technology-led research but our view is that cell biologists, in particular, should be proud of their 'progress through technology'. The 'cell theory' itself, arguably the oldest cornerstone in the theoretical foundations of biology, emerged because Hooke, van Leeuwenhoek and others had, more than a century earlier, pioneered the enabling technology--the microscope. We develop this theme with reference to our own field of research: the locomotion of cultured tissue cells.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Movement / physiology*
  • Computers
  • History, 16th Century
  • History, 17th Century
  • History, 18th Century
  • History, 19th Century
  • History, 20th Century
  • History, 21st Century
  • Microscopy / history*