VioC is a non-heme iron, alpha-ketoglutarate-dependent oxygenase that catalyzes the formation of 3S-hydroxy-L-arginine during viomycin biosynthesis

Chembiochem. 2004 Sep 6;5(9):1274-7. doi: 10.1002/cbic.200400082.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antibiotics, Antitubercular / biosynthesis*
  • Bacterial Proteins
  • Chromatography, High Pressure Liquid
  • Cloning, Molecular
  • Cosmids / genetics
  • DNA, Bacterial / biosynthesis
  • DNA, Bacterial / genetics
  • Electrophoresis, Polyacrylamide Gel
  • Hydroxylation
  • Nocardia / enzymology
  • Nocardia / metabolism
  • Nonheme Iron Proteins / metabolism*
  • Oxygenases / metabolism*
  • Recombinant Proteins / biosynthesis
  • Recombinant Proteins / isolation & purification
  • Reverse Transcriptase Polymerase Chain Reaction
  • Streptomyces / enzymology
  • Streptomyces / metabolism
  • Viomycin / biosynthesis*

Substances

  • Antibiotics, Antitubercular
  • Bacterial Proteins
  • DNA, Bacterial
  • Nonheme Iron Proteins
  • Recombinant Proteins
  • Oxygenases
  • vioC protein, Chromobacterium violaceum
  • Viomycin