Rhabdomyolysis connected with the use of bupropion

Scand J Prim Health Care. 2004 Sep;22(3):191-2. doi: 10.1080/02813430310000979.


Objective: To report an observation dealing with a possible side effect of a smoking cessation drug.

Design: A case report. STUDY PERSON: A 34-year old man who had been treated with slow-release bupropion for smoking cessation.

Observation: After 5 days of treatment the patient suffered severe muscular pain and the diagnosis of rhabdomyolysis was confirmed.

Conclusion: Rhabdomyolysis is a rare complication when treating with slow-release bupropion for smoking cessation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bupropion / adverse effects*
  • Humans
  • Male
  • Rhabdomyolysis / chemically induced*
  • Smoking / drug therapy*
  • Smoking Cessation / methods


  • Bupropion