Post-infectious acute renal failure due to calciphylaxis--when processes go the wrong way round

J Nephrol. Jul-Aug 2004;17(4):575-9.

Abstract

Calciphylaxis is a rare life threatening disorder of small- and medium-sized vessel calcification that leads to cutaneous necrosis. While its pathogenesis is uncertain, nearly all cases have been described in patients with end-stage renal disease (ESRD) on dialysis or following renal transplantation which is why the lesion has also been referred to as calcific uremic arteriolopathy. We describe a patient with alcoholic cirrhosis and normal renal function who developed calciphylaxis. Due to infected cutaneous lesions, he developed an acute post-infectious glomerulonephritis with extra capillary proliferation.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / drug therapy
  • Acute Kidney Injury / etiology*
  • Acute Kidney Injury / pathology
  • Biopsy, Needle
  • Calciphylaxis / complications*
  • Calciphylaxis / diagnostic imaging*
  • Disease Progression
  • Fatal Outcome
  • Humans
  • Immunohistochemistry
  • Immunosuppressive Agents / therapeutic use
  • Kidney Function Tests
  • Leg Ulcer / complications*
  • Leg Ulcer / diagnosis
  • Liver Cirrhosis, Alcoholic / complications
  • Liver Cirrhosis, Alcoholic / diagnosis*
  • Male
  • Middle Aged
  • Radionuclide Imaging
  • Risk Assessment
  • Severity of Illness Index

Substances

  • Immunosuppressive Agents