A pilot study of functional magnetic resonance imaging brain correlates of deception in healthy young men

J Neuropsychiatry Clin Neurosci. Summer 2004;16(3):295-305. doi: 10.1176/jnp.16.3.295.

Abstract

We hypothesized that specific brain regions would activate during deception, and these areas would correlate with changes in electrodermal activity (EDA). Eight men were asked to find money hidden under various objects. While functional MRI images were acquired and EDA was recorded, the subjects gave both truthful and deceptive answers regarding the money's location. The group analysis revealed significant activation during deception in the orbitofrontal cortex (OFCx) and anterior cingulate (AC), but individual results were not consistent. Individually and as a group, EDA correlated with blood flow changes in the OFCx and AC. Specific brain regions were activated during deception, but the present technique lacks good predictive power for individuals.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Brain / anatomy & histology
  • Brain / blood supply
  • Brain / physiology*
  • Brain Mapping
  • Deception*
  • Female
  • Frontal Lobe / blood supply
  • Frontal Lobe / physiology
  • Gyrus Cinguli / blood supply
  • Gyrus Cinguli / physiology
  • Humans
  • Image Processing, Computer-Assisted
  • Individuality
  • Lie Detection
  • Magnetic Resonance Imaging / methods*
  • Male
  • Neuropsychological Tests
  • Oxygen / blood
  • Pilot Projects

Substances

  • Oxygen