Connexins: gaps in our knowledge of vascular function

Physiology (Bethesda). 2004 Oct;19:277-84. doi: 10.1152/physiol.00008.2004.


Gap junctions are common features in the vasculature, long thought to provide a pathway for cell-cell signaling. Emerging understanding of the gap-junctional proteins (connexins) and new tools for their investigation now offer the opportunity to explore the vital role that the gap junctions may play in cardiovascular homeostasis and pathophysiology.

Publication types

  • Review

MeSH terms

  • Animals
  • Blood Vessels / physiology*
  • Connexins / physiology*
  • Gap Junctions / physiology*
  • Humans


  • Connexins