Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2004 Sep;42(3):145-8.
doi: 10.3347/kjp.2004.42.3.145.

Variation of nuclear and mitochondrial DNAs in Korean and Chinese isolates of Clonorchis sinensis

Affiliations
Comparative Study

Variation of nuclear and mitochondrial DNAs in Korean and Chinese isolates of Clonorchis sinensis

Soo-Ung Lee et al. Korean J Parasitol. 2004 Sep.

Abstract

We compared the DNA sequence difference of isolates of Clonorchis sinensis from one Korean (Kimhae) and two Chinese areas (Guangxi and Shenyang). The sequences of nuclear rDNA (18S, internal transcribed spacer 1 and 2: ITS1 and ITS2) and mitochondrial DNA (cytochrome c oxidase subunit 1: cox1) were compared. A very few intraspecific nucleotide substitution of the 18S, ITS1, ITS2 and cox1 was found among three isolates of C. sinensis and a few nucleotide insertion and deletion of ITS1 were detected. The 18S, ITS1, ITS2 and cox1 sequences were highly conserved among three isolates. These findings indicated that the Korean and two Chinese isolates are similar at the DNA sequence level.

PubMed Disclaimer

Comment in

Similar articles

Cited by

References

    1. Ando K, Sithithaworn P, Nuchjunggreed C, et al. Nucleotide sequence of mitochondrial COI and ribosomal ITSII of Opisthorchis viverrini in Northeast Thailand. Southeast Asian J Trop Med Public Health. 2001;32:17–22. - PubMed
    1. Barker SC, Blair D. Molecular phylogeny of Schistosoma species supports traditional groupings within the genus. J Parasitol. 1996;82:292–298. - PubMed
    1. Bowles J, Blair D, McManus DP. Genetic variants within the genus Echinococcus identified by mitochondrial DNA sequencing. Mol Biochem Parasitol. 1992;54:165–173. - PubMed
    1. Bowles J, Blair D, McManus DP. A molecular phylogeny of the human schistosomes. Mol Phylogenet Evol. 1995;4:103–109. - PubMed
    1. Bowles J, Hope M, Tiu WU, Liu X, McManus DP. Nuclear and mitochondrial genetic markers highly conserved between Chinese and Philippine Schistosoma japonicum. Acta Trop. 1993;55:217–229. - PubMed

Publication types

MeSH terms

LinkOut - more resources