The C. elegans genome sequencing project: a beginning

Nature. 1992 Mar 5;356(6364):37-41. doi: 10.1038/356037a0.


The long-term goal of this project is the elucidation of the complete sequence of the Caenorhabditis elegans genome. During the first year methods have been developed and a strategy implemented that is amenable to large-scale sequencing. The three cosmids sequenced in this initial phase are surprisingly rich in genes, many of which have mammalian homologues.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Base Sequence
  • Caenorhabditis / genetics*
  • Chromosome Mapping
  • Cosmids / genetics
  • Gene Library
  • Genome*