Muscle dysfunction versus wear and tear as a cause of exercise related osteoarthritis: an epidemiological update

Br J Sports Med. 2004 Oct;38(5):526-35. doi: 10.1136/bjsm.2003.011262.

Abstract

There are two main hypotheses for the cause of exercise related osteoarthritis: wear and tear of the articular cartilage and muscle dysfunction. This is a review of the clinical literature to see which hypothesis has the greatest support. Clinical studies support the muscle dysfunction hypothesis over the wear and tear hypothesis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Athletic Injuries / complications*
  • Athletic Injuries / physiopathology
  • Cartilage, Articular / injuries*
  • Cartilage, Articular / physiopathology
  • Epidemiologic Methods
  • Exercise / physiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Muscular Diseases / complications*
  • Muscular Diseases / physiopathology
  • Osteoarthritis / etiology*
  • Osteoarthritis / physiopathology
  • Running / injuries
  • Soccer / injuries