Condom use and other factors affecting penile human papillomavirus detection in men attending a sexually transmitted disease clinic

Sex Transm Dis. 2004 Oct;31(10):601-7. doi: 10.1097/01.olq.0000140012.02703.10.


Background and objectives: Human papillomavirus (HPV) is the primary cause of cervical, anal, and other anogenital cancers, but risk factors for penile HPV detection in men have not been well-characterized.

Goal: The goal of this study was to identify correlates of penile HPV detection in ethnically diverse men attending a sexually transmitted disease clinic.

Study: A cross-sectional investigation was conducted among 393 men. Participants completed a risk-factor questionnaire and underwent testing for penile HPV DNA. Presence of HPV DNA was assessed using polymerase chain reaction with PGMY primers and reverse line blot genotyping. Logistic regression analyses were conducted to identify variables associated with any-type, oncogenic, and nononcogenic HPV.

Results: Circumcision was associated with reduced risk for oncogenic, nononcogenic, and overall HPV. Regular condom use was associated with reduced risk for oncogenic and overall HPV.

Conclusion: These findings, if confirmed by other studies, could impact public health practices and messages regarding HPV.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Arizona / epidemiology
  • Circumcision, Male
  • Condoms / statistics & numerical data*
  • Cross-Sectional Studies
  • DNA Primers
  • DNA, Viral / analysis
  • Humans
  • Male
  • Middle Aged
  • Papillomaviridae / genetics
  • Papillomaviridae / isolation & purification
  • Papillomavirus Infections / epidemiology*
  • Papillomavirus Infections / etiology
  • Papillomavirus Infections / prevention & control
  • Penis / virology
  • Polymerase Chain Reaction
  • Risk Factors
  • Sexually Transmitted Diseases / epidemiology*
  • Sexually Transmitted Diseases / etiology
  • Sexually Transmitted Diseases / prevention & control
  • Surveys and Questionnaires
  • Tumor Virus Infections / epidemiology*
  • Tumor Virus Infections / etiology
  • Tumor Virus Infections / prevention & control


  • DNA Primers
  • DNA, Viral