Abstract
Of 99 patients on ergot-derived dopamine agonists informed about possible long-term side effects, switching to a nonergot was undertaken in 88 (89%). There were adverse events in 26%. After 11 months, 82% were on their switch agonist and 93% were on any agonist. Switching dopamine agonists is feasible in this population.
MeSH terms
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Adult
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Adverse Drug Reaction Reporting Systems
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Antiparkinson Agents / administration & dosage*
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Antiparkinson Agents / adverse effects
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Benzothiazoles
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Bromocriptine / administration & dosage
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Bromocriptine / adverse effects
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Cabergoline
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Domperidone / administration & dosage
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Domperidone / adverse effects
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Dopamine Agonists / administration & dosage*
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Dopamine Agonists / adverse effects
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Dose-Response Relationship, Drug
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Drug Administration Schedule
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Drug Therapy, Combination
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Ergolines / administration & dosage
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Ergolines / adverse effects
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Ergot Alkaloids / administration & dosage*
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Ergot Alkaloids / adverse effects
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Feasibility Studies
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Female
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Follow-Up Studies
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Humans
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Indoles / administration & dosage
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Indoles / adverse effects
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Levodopa / administration & dosage
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Levodopa / adverse effects
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Male
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Middle Aged
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Parkinson Disease / diagnosis
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Parkinson Disease / drug therapy*
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Pergolide / administration & dosage
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Pergolide / adverse effects
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Pramipexole
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Therapeutic Equivalency
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Thiazoles / administration & dosage
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Thiazoles / adverse effects
Substances
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Antiparkinson Agents
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Benzothiazoles
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Dopamine Agonists
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Ergolines
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Ergot Alkaloids
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Indoles
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Thiazoles
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ropinirole
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Pergolide
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Bromocriptine
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Levodopa
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Domperidone
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Pramipexole
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Cabergoline