Abstract
Serum marker KL-6 antigen has been reported to be a valuable indicator of the disease activity of interstitial pneumonia. It is not clear how sensitive the serum KL-6 antigen level is in reflecting histologic changes in lung tissues. We report here the results of serial measurements of serum KL-6 antigen in a 76-year-old male patient with radiation pneumonia. Serum KL-6 antigen levels were more sensitive than lactate dehydrogenase and procollagen type III N-terminal peptide. The level of serum KL-6 antigen appears to reflect the histologic changes of the lung more sensitively than does C-reactive protein.
MeSH terms
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Aged
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Antigens / blood*
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Antigens, Neoplasm
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Biomarkers / blood
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C-Reactive Protein / analysis
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Glycoproteins*
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Humans
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L-Lactate Dehydrogenase / blood
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Lung Neoplasms / radiotherapy
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Male
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Mucin-1
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Mucins
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Peptide Fragments / blood
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Procollagen / blood
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Pulmonary Fibrosis / diagnosis*
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Pulmonary Fibrosis / diagnostic imaging
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Pulmonary Fibrosis / etiology
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Radiation Injuries / diagnosis*
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Radiography
Substances
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Antigens
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Antigens, Neoplasm
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Biomarkers
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Glycoproteins
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MUC1 protein, human
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Mucin-1
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Mucins
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Peptide Fragments
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Procollagen
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procollagen Type III-N-terminal peptide
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C-Reactive Protein
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L-Lactate Dehydrogenase