We analyzed the results of high-pass resolution perimetry on normal eyes, eyes with ocular hypertension, and eyes with primary open-angle glaucoma. The subjects were matched for age and lens density. We controlled for refraction, visual acuity, pupil size, miotic medications, and learning effects. Under these conditions the glaucomatous eyes showed a significant reduction in overall resolution threshold compared to both normal (P less than or equal to .01) and hypertensive eyes (P less than .01). The hypertensive eyes were not significantly different from normal. Standard increment threshold fields and high-pass resolution visual fields had an agreement of abnormality of 67%. Resolution perimetry showed a 92% agreement with standard perimetry in the location of the defect, when the defect was apparent on both tests. These results indicated that resolution perimetry may be useful for diagnosis and management of primary open-angle glaucoma.