Localisation of the gene for the major intrinsic protein of eye-lens-fibre cell membranes to mouse chromosome 10 by in situ hybridisation

Cytogenet Cell Genet. 1992;59(4):300-2. doi: 10.1159/000133274.

Abstract

The gene encoding the major intrinsic protein (Mip) of eye-lens-fibre cell membranes has been assigned to region D1 of mouse Chromosome 10 by in situ hybridisation of a cDNA for rat MIP to G-banded metaphase chromosomes. The mouse Mip gene maps within or near to a segment homoeologous with human chromosome 12q and may be linked to the Cat locus at the distal end of mouse Chromosome 10.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Aquaporins
  • Cell Membrane / metabolism
  • Chromosome Mapping
  • Eye Proteins / genetics*
  • Lens, Crystalline / metabolism*
  • Lens, Crystalline / ultrastructure
  • Membrane Glycoproteins*
  • Mice
  • Nucleic Acid Hybridization

Substances

  • Aquaporins
  • Eye Proteins
  • Membrane Glycoproteins
  • aquaporin 0