Analysis of a Nicotiana plumbaginifolia cDNA encoding a novel small GTP-binding protein

FEBS Lett. 1992 Mar 16;299(3):287-90. doi: 10.1016/0014-5793(92)80133-2.


Small GTP-binding proteins belonging to the Ras superfamily have been found in evolutionarily divergent organisms. Here, we report the isolation and analysis of a cDNA encoding a putative small GTP-binding protein, designated Rhn1, from the plant, Nicotiana plumbaginifolia. The 21.8-kDa protein has 60% amino acid similarity with the mammalian Rab5 proteins. The Rhn1 protein is encoded by a small multigene family. Northern analysis shows the highest steady-state mRNA levels to be in roots and flowers. Furthermore, the Rhn1 protein has 80% amino acid similarity with an Arabidopsis small GTP-binding protein, designated Rha1.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Cell Differentiation
  • GTP-Binding Proteins / genetics*
  • Gene Expression
  • Molecular Sequence Data
  • Multigene Family / genetics
  • Plants, Toxic*
  • Sequence Homology, Nucleic Acid
  • Tobacco / genetics*


  • GTP-Binding Proteins

Associated data

  • GENBANK/S90294
  • GENBANK/S90296
  • GENBANK/S90298
  • GENBANK/X64941
  • GENBANK/X65499
  • GENBANK/X65500
  • GENBANK/X65501
  • GENBANK/X65502
  • GENBANK/X65503
  • GENBANK/X65504