The promise of functional genomics: completing the encyclopedia of a cell

Curr Opin Microbiol. 2004 Oct;7(5):546-54. doi: 10.1016/j.mib.2004.08.015.

Abstract

Genome sequencing provides complete parts lists of organisms. This presents the obvious challenge of determining how each gene contributes to the life of the organism. This task seems increasingly feasible; however, progress to date suggests that increased interaction between systematic efforts and individual investigators will be critical to completing the encyclopedia of the yeast cell.

Publication types

  • Review

MeSH terms

  • Gene Expression Regulation, Fungal
  • Genes, Fungal
  • Genome, Fungal*
  • Genomics*
  • Protein Interaction Mapping*
  • Proteome*
  • Proteomics
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae / physiology*
  • Saccharomyces cerevisiae Proteins / physiology

Substances

  • Proteome
  • Saccharomyces cerevisiae Proteins