The promise of functional genomics: completing the encyclopedia of a cell

Curr Opin Microbiol. 2004 Oct;7(5):546-54. doi: 10.1016/j.mib.2004.08.015.


Genome sequencing provides complete parts lists of organisms. This presents the obvious challenge of determining how each gene contributes to the life of the organism. This task seems increasingly feasible; however, progress to date suggests that increased interaction between systematic efforts and individual investigators will be critical to completing the encyclopedia of the yeast cell.

Publication types

  • Review

MeSH terms

  • Gene Expression Regulation, Fungal
  • Genes, Fungal
  • Genome, Fungal*
  • Genomics*
  • Protein Interaction Mapping*
  • Proteome*
  • Proteomics
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae / physiology*
  • Saccharomyces cerevisiae Proteins / physiology


  • Proteome
  • Saccharomyces cerevisiae Proteins