Practice parameter: treatment of postherpetic neuralgia: an evidence-based report of the Quality Standards Subcommittee of the American Academy of Neurology

Neurology. 2004 Sep 28;63(6):959-65. doi: 10.1212/01.wnl.0000140708.62856.72.

Abstract

A systematic review of the literature on postherpetic neuralgia was performed. The authors identified studies using the National Library of Medicine's Medline database and Cochrane Library database. The authors determined absolute reduction rate, number needed to treat (NNT), 95% CI for NNT, and number needed to harm (NNH) for successful therapies of postherpetic neuralgia. Tricyclic antidepressants, gabapentin, pregabalin, opioids, and lidocaine patch were found to be effective in reducing the pain of postherpetic neuralgia.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Acupuncture Analgesia
  • Administration, Cutaneous
  • Amines / administration & dosage
  • Amines / adverse effects
  • Amines / therapeutic use
  • Analgesics / administration & dosage
  • Analgesics / adverse effects
  • Analgesics / classification
  • Analgesics / therapeutic use*
  • Analgesics, Opioid / administration & dosage
  • Analgesics, Opioid / therapeutic use
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use
  • Anticonvulsants / administration & dosage
  • Anticonvulsants / therapeutic use
  • Antidepressive Agents, Tricyclic / administration & dosage
  • Antidepressive Agents, Tricyclic / adverse effects
  • Antidepressive Agents, Tricyclic / therapeutic use
  • Antiviral Agents / therapeutic use
  • Clinical Trials as Topic
  • Cyclohexanecarboxylic Acids / administration & dosage
  • Cyclohexanecarboxylic Acids / adverse effects
  • Cyclohexanecarboxylic Acids / therapeutic use
  • Double-Blind Method
  • Drug Evaluation
  • Evidence-Based Medicine
  • Excitatory Amino Acid Antagonists / administration & dosage
  • Excitatory Amino Acid Antagonists / therapeutic use
  • Forecasting
  • Gabapentin
  • Herpes Zoster / complications*
  • Herpes Zoster / drug therapy
  • Humans
  • Iontophoresis
  • Lidocaine / administration & dosage
  • Lidocaine / therapeutic use
  • Neuralgia / drug therapy*
  • Neuralgia / etiology
  • Neuralgia / prevention & control
  • Neuralgia / therapy
  • Pregabalin
  • Randomized Controlled Trials as Topic
  • Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors
  • gamma-Aminobutyric Acid / administration & dosage
  • gamma-Aminobutyric Acid / adverse effects
  • gamma-Aminobutyric Acid / analogs & derivatives*
  • gamma-Aminobutyric Acid / therapeutic use

Substances

  • Amines
  • Analgesics
  • Analgesics, Opioid
  • Anti-Inflammatory Agents
  • Anticonvulsants
  • Antidepressive Agents, Tricyclic
  • Antiviral Agents
  • Cyclohexanecarboxylic Acids
  • Excitatory Amino Acid Antagonists
  • Receptors, N-Methyl-D-Aspartate
  • Pregabalin
  • gamma-Aminobutyric Acid
  • Gabapentin
  • Lidocaine