Desquamative interstitial pneumonia and hepatitis C virus infection: a rare association

South Med J. 2004 Sep;97(9):890-3. doi: 10.1097/01.SMJ.0000136259.92633.E8.


Extrahepatic manifestations of hepatitis C virus (HCV) infection are common. The authors report the unusual occurrence of desquamative interstitial pneumonia (DIP) in a patient with HCV. An immunologic response to HCV infection may have a role in the pathogenesis of DIP in patients with chronic HCV. Since DIP is treatable, HCV patients with pulmonary infiltrates should be thoroughly investigated for this disorder. In our experience, the use of steroids in HCV-associated DIP improved the patient's respiratory status without increasing the viral load.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Female
  • Glucocorticoids / therapeutic use
  • Hepatitis C, Chronic / complications*
  • Humans
  • Lung Diseases, Interstitial / diagnostic imaging
  • Lung Diseases, Interstitial / drug therapy
  • Lung Diseases, Interstitial / etiology*
  • Male
  • Middle Aged
  • Radiography


  • Glucocorticoids