Intestinal mucus alters the ability of probiotic bacteria to bind aflatoxin B1 in vitro

Appl Environ Microbiol. 2004 Oct;70(10):6306-8. doi: 10.1128/AEM.70.10.6306-6308.2004.


Several probiotics are known to bind aflatoxin B(1) (AFB(1)) to their surfaces and to adhere to intestinal mucus. In this study, preincubation of two probiotic preparations with either AFB(1) or mucus reduced the subsequent surface binding of mucus and AFB(1), respectively, in a strain-dependent manner.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aflatoxin B1 / metabolism*
  • Aflatoxin B1 / toxicity
  • Animals
  • Food Contamination
  • In Vitro Techniques
  • Intestinal Mucosa / metabolism*
  • Intestines / microbiology*
  • Kinetics
  • Lactobacillus / metabolism
  • Mucus / metabolism*
  • Mucus / microbiology*
  • Probiotics*
  • Propionibacterium / metabolism
  • Sus scrofa


  • Aflatoxin B1