Mutagenicity of CORAGRAF and REKAGRAF in the Ames test

A H Suzina; A Azlina; O Shamsuria; A R Samsudin

Mutagenicity of CORAGRAF and REKAGRAF in the Ames test

Med J Malaysia. 2004 May:59 Suppl B:105-6.

Authors

A H Suzina¹, A Azlina, O Shamsuria, A R Samsudin

Affiliation

¹ School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.

PMID: 15468840

Abstract

Mutagenicity of CORAGRAF (natural coral) and REKAGRAF (hydroxyapatite) was tested in Ames test with and without an external metabolic activation system (S9). The test revealed no mutagenic activity of both locally produced osseous substitutes.

Publication types

Comparative Study

MeSH terms

Base Pair Mismatch / drug effects
Biotransformation / physiology
Bone Substitutes / toxicity*
Calcium Carbonate / toxicity*
Chromosome Aberrations
Escherichia coli / genetics
Humans
Hydroxyapatites / toxicity*
Materials Testing*
Mutagenicity Tests*
Salmonella typhimurium / genetics

Substances

Bone Substitutes
Hydroxyapatites
Calcium Carbonate