Mechanisms of Androgen-Refractory Prostate Cancer

N Engl J Med. 2004 Oct 7;351(15):1488-90. doi: 10.1056/NEJMp048178.

Publication types

  • Comment

MeSH terms

  • Androgens / metabolism
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Apoptosis
  • Docetaxel
  • Drug Resistance, Neoplasm / physiology
  • Gene Amplification
  • Humans
  • Male
  • Mutation
  • Neoplasms, Hormone-Dependent / metabolism*
  • Prostatic Neoplasms / drug therapy
  • Prostatic Neoplasms / metabolism*
  • Receptors, Androgen / genetics
  • Receptors, Androgen / metabolism*
  • Signal Transduction
  • Taxoids / administration & dosage

Substances

  • Androgens
  • Receptors, Androgen
  • Taxoids
  • Docetaxel