A case of shaker dog disease in a miniature dachshund

J Vet Med Sci. 2004 Sep;66(9):1159-60. doi: 10.1292/jvms.66.1159.


A male miniature Dachshund, twenty-two months of age, was referred with paroxysmal generalized tremors as a main clinical sign. There were no abnormalities in the neurological examination except the lack of bilateral menace responses, and in the magnetic resonance imaging of its brain. Analysis of cerebro-spinal fluid revealed a slight rise in protein concentration and an increase in the number of cells. This case with brown hair was diagnosed as the shaker dog disease, which has also been well known as "little white shakers" syndrome due to being found in small dogs with white hair, because the clinical signs were exactly analogous to the shaker dog disease, and the generalized tremors disappeared on the first day after the administration of prednisolone and diazepam.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Animals
  • Brain / pathology
  • Cerebrospinal Fluid Proteins / analysis*
  • Diazepam / therapeutic use
  • Dog Diseases / drug therapy*
  • Dog Diseases / pathology*
  • Dogs
  • Male
  • Movement Disorders / drug therapy
  • Movement Disorders / pathology
  • Movement Disorders / veterinary*
  • Prednisolone / therapeutic use


  • Cerebrospinal Fluid Proteins
  • Prednisolone
  • Diazepam