Evolvable social agents for bacterial systems modeling

IEEE Trans Nanobioscience. 2004 Sep;3(3):208-16. doi: 10.1109/tnb.2004.833701.

Abstract

We present two approaches to the individual-based modeling (IbM) of bacterial ecologies and evolution using computational tools. The IbM approach is introduced, and its important complementary role to biosystems modeling is discussed. A fine-grained model of bacterial evolution is then presented that is based on networks of interactivity between computational objects representing genes and proteins. This is followed by a coarser grained agent-based model, which is designed to explore the evolvability of adaptive behavioral strategies in artificial bacteria represented by learning classifier systems. The structure and implementation of the two proposed individual-based bacterial models are discussed, and some results from simulation experiments are presented, illustrating their adaptive properties.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Physiological / physiology
  • Artificial Intelligence*
  • Bacterial Physiological Phenomena*
  • Bacterial Proteins / physiology*
  • Computer Simulation
  • Directed Molecular Evolution / methods*
  • Environment
  • Gene Expression Regulation / physiology*
  • Models, Biological*
  • Signal Transduction / physiology*
  • Systems Biology / methods

Substances

  • Bacterial Proteins