The vascular endothelial growth factor family and its receptors

Hematol Oncol Clin North Am. 2004 Oct;18(5):951-71, vii. doi: 10.1016/j.hoc.2004.06.004.

Abstract

This article focuses on describing the biology of vascular endothelial growth factor (VEGF) and its receptors as well as the regulation of their expression. A thorough understanding of the VEGF system is paramount in optimizing antiangiogenic therapies as a component of antineoplastic regimens.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Endothelium, Vascular / physiology
  • Humans
  • Neoplasms / blood supply
  • Neovascularization, Pathologic
  • Neovascularization, Physiologic
  • Receptors, Vascular Endothelial Growth Factor / physiology*
  • Vascular Endothelial Growth Factor A / classification
  • Vascular Endothelial Growth Factor A / physiology*

Substances

  • Vascular Endothelial Growth Factor A
  • Receptors, Vascular Endothelial Growth Factor