Molecular Targeting: PI3 Kinase Pathway

Ann Oncol. 2004;15 Suppl 4:iv233-9. doi: 10.1093/annonc/mdh932.

Publication types

  • Review

MeSH terms

  • 3-Phosphoinositide-Dependent Protein Kinases
  • Antibiotics, Antineoplastic / pharmacology
  • Antibiotics, Antineoplastic / therapeutic use
  • Apoptosis
  • Cell Proliferation
  • Cell Survival
  • Humans
  • Neoplasms / drug therapy*
  • Neoplasms / genetics*
  • Phosphatidylinositol 3-Kinases / genetics*
  • Phosphatidylinositol 3-Kinases / pharmacology*
  • Protein-Serine-Threonine Kinases / genetics*
  • Protein-Serine-Threonine Kinases / pharmacology*
  • Proto-Oncogene Proteins / genetics*
  • Proto-Oncogene Proteins / pharmacology*
  • Proto-Oncogene Proteins c-akt
  • Signal Transduction
  • Sirolimus / pharmacology
  • Sirolimus / therapeutic use

Substances

  • Antibiotics, Antineoplastic
  • Proto-Oncogene Proteins
  • Phosphatidylinositol 3-Kinases
  • 3-Phosphoinositide-Dependent Protein Kinases
  • Protein-Serine-Threonine Kinases
  • Proto-Oncogene Proteins c-akt
  • Sirolimus