Psoriasis remission after laparoscopic Roux-en-Y gastric bypass for morbid obesity

Obes Surg. 2004 Sep;14(8):1132-4. doi: 10.1381/0960892041975569.


Background: Psoriasis is a chronic skin disease characterized by epithelial hyperplasia and an accelerated rate of epithelial turnover affecting approximately 1-3% of the population. Exogenous and endogenous factors including morbid obesity can increase the morbidity of psoriasis.

Case report: A 55-year-old male, who weighed 131 kg with BMI 41 kg/m2, underwent laparoscopic Roux-en-Y gastric bypass (LRYGBP). He had a 15-year duration of severe psoriasis and was being medically treated. At 12 months after LRYGBP, he had lost 39 kg (68% EWL), and had complete resolution of the psoriasis and had discontinued all preoperative medications related to the disease. At 2 years after LRYGBP, psoriasis has not recurred.

Conclusion: Weight loss after LRYGBP should be considered as a strategy in the treatment of severe psoriasis in morbidly obese patients.

Publication types

  • Case Reports

MeSH terms

  • Anastomosis, Roux-en-Y
  • Gastric Bypass / methods*
  • Humans
  • Laparoscopy
  • Male
  • Middle Aged
  • Obesity, Morbid / complications
  • Obesity, Morbid / surgery*
  • Psoriasis / complications
  • Psoriasis / therapy*
  • Remission Induction
  • Treatment Outcome
  • Weight Loss