Therapy for recurrent malignant glioma in adults

Expert Rev Anticancer Ther. 2004 Oct;4(5):759-82. doi: 10.1586/14737140.4.5.759.


Malignant gliomas are the most common form of primary brain tumors in adults. Although the prognosis remains poor, there has been recent progress in the treatment of these tumors. Standard therapy for patients with this disease will be reviewed, together with more novel approaches such as targeted molecular therapies, angiogenesis inhibitors, immunotherapies, gene therapies and intratumoral therapies.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Age Factors
  • Angiogenesis Inhibitors / therapeutic use*
  • Brain Neoplasms / drug therapy*
  • Brain Neoplasms / genetics*
  • Brain Neoplasms / pathology
  • Clinical Trials as Topic
  • Genetic Therapy*
  • Glioma / drug therapy*
  • Glioma / genetics*
  • Glioma / pathology
  • Humans
  • Immunotherapy
  • Neoplasm Recurrence, Local / drug therapy*
  • Neoplasm Recurrence, Local / genetics*
  • Neoplasm Recurrence, Local / pathology
  • Prognosis


  • Angiogenesis Inhibitors