T-cell epitope peptide vaccines

Expert Rev Vaccines. 2004 Oct;3(5):563-75. doi: 10.1586/14760584.3.5.563.


T-cell immunotherapy is a promising treatment option for cancer. The identification of tumor antigens that are recognized by the immune system has allowed for the generation of vaccines for various malignancies. Due to the ease of manufacturing and characterizating peptide-based vaccines they have been used to stimulate antitumor T-cells. This article will review the use of peptide-based vaccines for the treatment of cancer by inducing antitumor T-lymphocyte responses.

Publication types

  • Review

MeSH terms

  • Adjuvants, Immunologic
  • Animals
  • Antigens, Neoplasm / immunology*
  • Cancer Vaccines / therapeutic use*
  • Dendritic Cells / immunology
  • Epitopes, T-Lymphocyte / immunology*
  • Humans
  • Immunotherapy*
  • Neoplasms / immunology*
  • Neoplasms / therapy
  • T-Lymphocytes / immunology
  • Vaccines, Subunit / therapeutic use


  • Adjuvants, Immunologic
  • Antigens, Neoplasm
  • Cancer Vaccines
  • Epitopes, T-Lymphocyte
  • Vaccines, Subunit