Small GTPases in Vesicle Trafficking

Curr Opin Plant Biol. 2004 Dec;7(6):694-700. doi: 10.1016/j.pbi.2004.09.014.


Plant small GTPases belonging to the Rop, Arf, and Rab families are regulators of vesicle trafficking. Rop GTPases regulate actin dynamics and modulate H(2)O(2) production in polar cell growth and pathogen defence. A candidate Rop GDP to Rop GTP exchange factor (RopGEF) SPIKE1 is involved in the morphogenesis of leaf epidermal cells. The ArfGEF GNOM regulates the endosomal recycling of the PIN proteins, which are involved in polar auxin transport. Intracellular localisation of small GTPases and functional studies using dominant mutant versions of Arf and Rab GTPases are defining novel plant-specific membrane compartments, especially those that participate in endosomal vesicle trafficking.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • ADP-Ribosylation Factors / metabolism
  • ADP-Ribosylation Factors / physiology
  • Biological Transport
  • Cell Polarity
  • GTP Phosphohydrolases / metabolism
  • GTP Phosphohydrolases / physiology*
  • Indoleacetic Acids / metabolism
  • Models, Biological
  • Plants / immunology
  • Plants / metabolism*
  • Signal Transduction
  • rab GTP-Binding Proteins / metabolism
  • rab GTP-Binding Proteins / physiology
  • rho GTP-Binding Proteins / metabolism
  • rho GTP-Binding Proteins / physiology


  • Indoleacetic Acids
  • GTP Phosphohydrolases
  • ADP-Ribosylation Factors
  • rab GTP-Binding Proteins
  • rho GTP-Binding Proteins