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Review
, 14 (20), R883-5

tRNA Maturation: RNA Polymerization Without a Nucleic Acid Template

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Review

tRNA Maturation: RNA Polymerization Without a Nucleic Acid Template

Alan M Weiner. Curr Biol.

Abstract

The CCA-adding enzyme, which builds and repairs the 3' terminal CCA sequence of tRNA, is the only RNA polymerase that can synthesize a defined nucleotide sequence without using a nucleic acid template. New cocrystal structures tell us how this remarkable enzyme works.

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