Ca2+ Depletion Induces Nuclear Clusterin, a Novel Effector of Apoptosis in Immortalized Human Prostate Cells

Cell Death Differ. 2005 Jan;12(1):101-4. doi: 10.1038/sj.cdd.4401491.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anoikis / drug effects
  • Anoikis / physiology
  • Apoptosis / drug effects
  • Apoptosis / physiology*
  • Calcium / antagonists & inhibitors
  • Calcium / deficiency*
  • Calcium / pharmacology
  • Caspase 3
  • Caspase 9
  • Caspase Inhibitors
  • Caspases / metabolism
  • Cell Line, Transformed
  • Cell Nucleus / metabolism*
  • Cell Proliferation / drug effects
  • Clusterin
  • Cytoplasm / metabolism
  • DNA Fragmentation / drug effects
  • Egtazic Acid / analogs & derivatives
  • Egtazic Acid / pharmacology
  • Epithelial Cells / drug effects
  • Epithelial Cells / metabolism
  • Glycoproteins / genetics
  • Glycoproteins / metabolism
  • Glycoproteins / physiology*
  • Humans
  • Male
  • Molecular Chaperones / genetics
  • Molecular Chaperones / metabolism
  • Molecular Chaperones / physiology*
  • Poly(ADP-ribose) Polymerases / metabolism
  • Prostate / cytology*
  • Prostate / metabolism
  • Protein Isoforms / genetics
  • Protein Isoforms / metabolism
  • Protein Isoforms / physiology
  • Protein Transport / drug effects
  • Transfection

Substances

  • CLU protein, human
  • Caspase Inhibitors
  • Clusterin
  • Glycoproteins
  • Molecular Chaperones
  • Protein Isoforms
  • 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester
  • Egtazic Acid
  • Poly(ADP-ribose) Polymerases
  • CASP3 protein, human
  • CASP9 protein, human
  • Caspase 3
  • Caspase 9
  • Caspases
  • Calcium