Clinical and genetic aspects of X-linked ectodermal dysplasia in the dog -- a review including three new spontaneous cases

Vet Dermatol. 2004 Oct;15(5):269-77. doi: 10.1111/j.1365-3164.2004.00407.x.


This review presents the clinical, dermato-histopathological and genetic features of canine X-linked ectodermal dysplasia in previously reported cases and in three new spontaneous cases. The condition is compared with anhidrotic ectodermal dysplasia in humans and, based on current genetic concepts, we suggest that the two conditions are caused by the same gene and, consequently, represent a single pathological entity that affects both humans and dogs.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Animals
  • Diagnosis, Differential
  • Dog Diseases / diagnosis*
  • Dog Diseases / genetics*
  • Dogs
  • Ectodermal Dysplasia / diagnosis
  • Ectodermal Dysplasia / genetics
  • Ectodermal Dysplasia / veterinary*
  • Genetic Linkage
  • Male
  • Pedigree
  • X Chromosome*