Advancement of biomarker discovery and validation through the HUPO plasma proteome project

Dis Markers. 2004;20(3):131-4. doi: 10.1155/2004/579363.


The Human Proteome Organization (HUPO) Plasma Proteome Project has mounted a Pilot Phase focussed on key problems essential for standardization of specimen collection, specimen handling, choice of fractionation and analysis technologies, and search engines and databases for protein identifications. This international collaboration will lay the groundwork for many large-scale clinical and epidemiological studies of health and disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Validation Study

MeSH terms

  • Biomarkers / blood*
  • Databases, Protein
  • Humans
  • International Cooperation
  • Pilot Projects
  • Proteomics / methods*
  • Proteomics / standards
  • Proteomics / trends


  • Biomarkers