Idiopathic hypercalcemia and eosinophilic fasciitis: a novel association

J Pediatr Endocrinol Metab. 2004 Sep;17(9):1251-4. doi: 10.1515/jpem.2004.17.9.1251.


A 15 year-old boy presented with moderate hypercalcemia (serum calcium 3.35 mmol/l) and eosinophilic fasciitis. An extensive search for a cause of hypercalcemia or underlying malignancy proved negative. Glucocorticoid treatment resulted in significant clinical improvement and resolution of the hypercalcemia. This report describes the novel association of hypercalcemia with eosinophilic fasciitis, with potential implications for the role of inflammatory mediators.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Blood Chemical Analysis
  • Eosinophilia / complications
  • Eosinophilia / diagnosis*
  • Fasciitis / complications
  • Fasciitis / diagnosis*
  • Follow-Up Studies
  • Glucocorticoids / therapeutic use*
  • Humans
  • Hypercalcemia / complications
  • Hypercalcemia / diagnosis*
  • Hypercalcemia / drug therapy*
  • Male
  • Risk Assessment
  • Severity of Illness Index
  • Treatment Outcome


  • Glucocorticoids