A search tool for identification and analysis of conserved sequence patterns in Saccharomyces spp. orthologous promoter

In Silico Biol. 2004;4(4):411-5.

Abstract

We describe a web-based resource to identify, search and analyze sequence patterns conserved in the multiple sequence alignments of orthologous promoters from closely related / distant Saccharomyces spp. The webtool interfaces with a database where conserved sequence patterns (greater than 4 bp) have been previously extracted from genome-wide promoter alignments, allowing one to carry out user-defined genome-wide searches for conserved sequences to assist in the discovery of novel promoter elements based on comparative genomics. The web-based server can be accessed at http://www2.imtech.res.in/ anand/sacch_prom_pat.html.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Computational Biology / methods
  • Conserved Sequence
  • Databases, Genetic
  • Genome, Fungal
  • Promoter Regions, Genetic / genetics*
  • Saccharomyces / genetics*
  • Sequence Analysis, DNA / methods*
  • Software*