HyPhy: hypothesis testing using phylogenies

Bioinformatics. 2005 Mar 1;21(5):676-9. doi: 10.1093/bioinformatics/bti079. Epub 2004 Oct 27.


The HyPhypackage is designed to provide a flexible and unified platform for carrying out likelihood-based analyses on multiple alignments of molecular sequence data, with the emphasis on studies of rates and patterns of sequence evolution.

Availability: http://www.hyphy.org

Contact: muse@stat.ncsu.edu

Supplementary information: HyPhydocumentation and tutorials are available at http://www.hyphy.org.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Algorithms*
  • Computer Simulation
  • Evolution, Molecular*
  • Models, Genetic*
  • Phylogeny*
  • Sequence Alignment / methods*
  • Sequence Analysis, Protein / methods*
  • Software*
  • User-Computer Interface*