Spontaneous regression of acquired immune deficiency syndrome-related, high-grade, extranodal non-Hodgkin's lymphoma

Cancer. 1992 Apr 1;69(7):1856-7. doi: 10.1002/1097-0142(19920401)69:7<1856::aid-cncr2820690730>3.0.co;2-q.


Spontaneous regression of low-grade non-Hodgkin's lymphoma often has been reported. Proposed mechanisms of this event have included concomitant infections and enhanced cellular and humoral antitumor responses by the host. Spontaneous regression of high-grade non-Hodgkin's lymphoma is rare and has never been reported in a patient with acquired immune deficiency syndrome (AIDS). The authors report a patient with spontaneous regression of AIDS-related non-Hodgkin's lymphoma and discuss the role of host immunity in mediating spontaneous regression.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibody Formation
  • Humans
  • Lymphoma, AIDS-Related* / immunology
  • Lymphoma, Non-Hodgkin* / immunology
  • Male
  • Neoplasm Regression, Spontaneous* / immunology