Angiosarcoma arising in the area of chronically lymphoedematous extremity is referred to as Stewart-Treves syndrome. In the world literature we can find about 400 cases of Stewart-Treves syndrome occurring after treatment for breast cancer. There are also occasional case reports of Stewart-Treves syndrome within chronically lymphoedematous upper extremity not related to breast cancer treatment and within chronically lymphoedematous leg. Treatment of choice is wide surgical resection with clear surgical margins. Adjuvant radiotherapy is advised. Treatment outcomes are generally poor. 5 year survival is estimated at 10%.