Genetic testing in hereditary melanoma

Hensin Tsao; Kristin Niendorf

doi:10.1016/j.jaad.2004.04.045

Genetic testing in hereditary melanoma

J Am Acad Dermatol. 2004 Nov;51(5):803-8. doi: 10.1016/j.jaad.2004.04.045.

Authors

Hensin Tsao¹, Kristin Niendorf

Affiliation

¹ Wellman Center for Photomedicine, Department of Dermatology, Boston, Massachusetts, USA.

PMID: 15523363
DOI: 10.1016/j.jaad.2004.04.045

Abstract

Advances in our understanding of molecular genetics bring about unique challenges in our ability to practice molecular medicine. With the availability of commercial testing for various genetic cancer syndromes, including hereditary melanoma, specific issues regarding its use and limitations require attention before full translation of this tool into the clinical setting.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Cyclin-Dependent Kinase 4
Cyclin-Dependent Kinases / genetics
Genes, p16 / physiology
Genetic Predisposition to Disease
Genetic Techniques*
Genetic Testing*
Humans
Melanoma / genetics*
Mutation
Proto-Oncogene Proteins / genetics
Skin Neoplasms / genetics*

Substances

Proto-Oncogene Proteins
CDK4 protein, human
Cyclin-Dependent Kinase 4
Cyclin-Dependent Kinases