Study of lubricant-induced changes in chronic snorers (SLICCS)

Otolaryngol Head Neck Surg. 2004 Nov;131(5):606-9. doi: 10.1016/j.otohns.2004.05.024.


Objective: The efficacy of many of the noninvasive treatments for snoring has not been evaluated in controlled trials. This paper seeks to evaluate the efficacy of an oil-based spray in the treatment of snoring, in a double-blinded, placebo-controlled, crossover trial using objective acoustic analysis and subjective questionnaires.

Study design and setting: Participants were randomized to use both oil-based oral spray (treatment) and water-based oral spray (placebo) during a two-night in-home study period. Questionnaires were completed by participant and bed-partner in addition to audio-tape recordings which were analyzed for frequency, duration, and mean energy of snoring.

Results: Greatest snoring rate demonstrated 30% = benefit; 40% = no change; 30% = adverse effect (n = 20). Percent time snoring yielded: 30% benefit; 15% no change; 55% adverse effect (n = 20). Study data results for mean energy were (n = 12): benefit = 17%, no change = 33%, adverse effect = 50%. Bed-partner observations (n = 17) demonstrated 37% = benefit; 38% = no change; 25% = adverse effect.

Conclusion/significance: Objective and subjective evaluation of the performance of the oil-based Snoreless spray in comparison to placebo demonstrated a lack of efficacy in snoring reduction.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acoustics / instrumentation
  • Administration, Topical
  • Adult
  • Chronic Disease
  • Cross-Over Studies
  • Double-Blind Method
  • Female
  • Humans
  • Lubrication
  • Male
  • Middle Aged
  • Oils / administration & dosage*
  • Snoring / diagnosis
  • Snoring / drug therapy*
  • Tape Recording
  • Treatment Outcome


  • Oils