Influence of perinatal conditions on C-reactive protein production

J Pediatr. 1992 Apr;120(4 Pt 1):621-4. doi: 10.1016/s0022-3476(05)82493-x.


C-reactive protein rises in blood in an acute-phase response in adults, children, and neonates. In a prospective study of the influence of perinatal asphyxia, premature rupture of membranes, hyperbilirubinemia, and respiratory distress syndrome on levels of C-reactive protein in the neonate, we detected no confounding effect on the rise of C-reactive protein level in infants with these pathologic perinatal conditions, as compared with the results of a control group.

MeSH terms

  • C-Reactive Protein / analysis*
  • Cerebral Hemorrhage / metabolism
  • Female
  • Fetal Distress / metabolism
  • Fetal Membranes, Premature Rupture / metabolism
  • Humans
  • Hyperbilirubinemia / metabolism
  • Infant, Newborn
  • Infant, Newborn, Diseases / metabolism*
  • Pregnancy
  • Prospective Studies
  • Reference Values
  • Respiratory Distress Syndrome, Newborn / metabolism


  • C-Reactive Protein