Intraoperative use of autologous platelet-rich and platelet-poor plasma for orthopedic surgery patients

AORN J. 2004 Oct;80(4):668-74, quiz 675-8. doi: 10.1016/s0001-2092(06)61320-3.


As use of autologous platelet-rich plasma (PRP) and platelet-poor plasma (PPP) increases for intraoperative care of a variety of patients, it is important for perioperative nurses to recognize their benefits. Autologous PRP may decrease postoperative drainage, reduce narcotic requirements, and facilitate an early return to mobility. Postoperatively, patients should experience fewer complications, recover more rapidly, and have a reduced hospital stay. This article defines autologous PRP and PPP, describes processing and application of PRP and PPP, and reports clinical outcomes of the use of platelet concentrate for a group of patients who underwent total knee arthroplasty.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial
  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Arthroplasty, Replacement, Knee / instrumentation
  • Arthroplasty, Replacement, Knee / methods*
  • Arthroplasty, Replacement, Knee / nursing*
  • Blood Platelets*
  • Centrifugation
  • Female
  • Gels
  • Humans
  • Intraoperative Care
  • Male
  • Middle Aged
  • Perioperative Nursing*
  • Plasma*
  • Treatment Outcome


  • Gels