High incidence of orbital malignant lymphoma in Japanese patients

Am J Ophthalmol. 2004 Nov;138(5):881-2. doi: 10.1016/j.ajo.2004.05.069.

Abstract

Purpose: To review 244 cases of orbital tumors to determine pathologic findings in Japanese patients.

Design: Observational case series.

Methods: We studied the pathology and origin of tumors in the orbit in 244 consecutive Japanese patients with orbital tumors at our institution from 1981 through 2002 (age 0 to 90 years, mean, 48.7 years; 114 men, 130 women).

Results: The most common tumors were lymphoproliferative diseases (n = 114, 42.5%), including malignant lymphoma (n = 59, 24.1%) and reactive lymphoid hyperplasia (n = 45, 18.4%), pleomorphic adenoma (n = 21, 8.6%), and cavernous hemangioma (n = 18, 7.4%).

Conclusion: The incidence of lymphoproliferative diseases, especially malignant lymphoma, was very high in Japanese patients.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Japan / epidemiology
  • Lymphoma / epidemiology*
  • Lymphoma / pathology
  • Male
  • Middle Aged
  • Orbital Neoplasms / epidemiology*
  • Orbital Neoplasms / pathology