The occurrence of Guillain-Barre syndrome within families

Neurology. 2004 Nov 9;63(9):1747-50. doi: 10.1212/01.wnl.0000143055.09646.31.


This report describes 12 Dutch families of which at least two members have had Guillain-Barre syndrome (GBS). The authors observed an earlier onset of GBS in successive generations. The occurrence of GBS within families suggests a role for genetic factors in the pathogenesis of GBS.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age of Onset
  • Aged
  • Child
  • Child, Preschool
  • Female
  • Genetic Predisposition to Disease*
  • Guillain-Barre Syndrome / diagnosis
  • Guillain-Barre Syndrome / epidemiology
  • Guillain-Barre Syndrome / genetics*
  • Humans
  • Infant, Newborn
  • Male
  • Middle Aged
  • Pedigree