Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2004 Dec;44(28):3411-8.
doi: 10.1016/j.visres.2004.09.001.

Characterization of Mouse Cortical Spatial Vision


Characterization of Mouse Cortical Spatial Vision

G T Prusky et al. Vision Res. .


Little is known about the spatial vision of mice or of the role the visual cortex plays in mouse visual perception. In order to provide baseline information upon which to evaluate the spatial vision of experimentally and genetically altered mice, we used the visual water task to assess the contrast sensitivity and grating acuity of normal C57BL/6 mice. We then ablated striate cortex (V1) bilaterally and re-measured the same visual functions. Intact mice displayed an inverse "U"-shaped contrast sensitivity curve with a maximum sensitivity near 0.2 cycles/degree (c/d). Grating acuity, measured either by discriminating a sine-wave grating from an equiluminant gray, or vertical from horizontal sine wave gratings, was near 0.55 c/d. Grating acuity and contrast sensitivity were reduced significantly following aspiration of V1. The mouse visual system exhibits fundamental mammalian characteristics, including the feature that striate cortex is involved in processing visual information with the highest sensitivity and spatial frequency.

Similar articles

See all similar articles

Cited by 73 articles

See all "Cited by" articles

LinkOut - more resources